产品名称 |
ATG5 Mouse Monoclonal Antibody(8B4) |
反应种属 |
H,R,M |
应用 |
IHC |
配方 |
PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. |
别称 |
APG5, APG5L, ASP, Autophagy protein 5 antibody |
储存 |
-20°C. Do not aliquot the antibody. |
推荐稀释比 |
IHC: 1:100-200
Optimal dilutions should be determined by the end user. |
特异性 |
The antibody can detects endogenous ATG5 proteins. |
背景信息 |
Autophagy is generally activated by conditions of nutrient deprivation but has also been associated with a number of physiological processes including development, differentiation, neurodegeneration, infection, and cancer. Formation of the autophagosome involves a ubiquitin-like conjugation system in which Atg12 is covalently bound to Atg5 and targeted to autophagosome vesicles. This conjugation reaction is mediated by the ubiquitin E1-like enzyme Atg7 and the E2-like enzyme Atg10. |
分子量 |
~55KD |
同型 |
IgG1 |
GeneID |
9494 |
理论分子量 |
55 |
SWISS |
Q9H1Y0 |
宿主物种 |
Mouse |
免疫原 |
Recombinant Protein |
克隆性 |
Monoclonal |