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货号:RP0007
Recombinant Human/Mouse/Rat Activin A
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规格:

50 μg

500 μg

价格:

¥4224

¥21504

货期: 3个工作日

产品属性/ Product Details
产品名称 Recombinant Human/Mouse/Rat Activin A 蛋白编号 P08476
产品别称 Inhibin beta A chain; INHBA; Activin A
产品描述 Recombinant Human Activin A is produced by our Mammalian expression system and the target gene encoding Gly311-Ser426 is expressed.
分子量 Mol Mass:13 KDa; APMol Mass:15 KDa, reducing conditions 剂型描述 Lyophilized from a 0.2 μm filtered solution of 4mM HCl.
内毒素 < 0.01 EU/µg as determined by LAL test. 纯度 Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
生物活性 Measured by its ability to induce SMAD signaling in 293-Activin A Res cells. The ED50 for this effect is 1.3 ng/ml. (Regularly tested)|Human intestinal organoids (ipsc source) were cultured with Activin A , BMP-4 , EGF , Wnt3a , Noggin, R-spondin 1 and FGF-4 . The organoids showed good morphology.
复溶 Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
保存条件 Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
产品背景 Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. Activins, members of the TGF-beta superfamily, are disulfide-linked dimeric proteins originally purified from gonadal fluids as proteins that stimulated pituitary follicle stimulating hormone (FSH) release. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Activins are homodimers or heterodimers of the various beta subunit isoforms, while inhibins are heterodimers of a unique alpha subunit and one of the various beta subunits.
  • Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
  • Measured by its ability to induce SMAD signaling in 293-Activin A Res cells. The ED50 for this effect is 1.3 ng/ml (Regularly tested).