产品名称 |
Recombinant Mouse G-CSF (C-6His) |
蛋白编号 |
P09920 |
产品别称 |
Granulocyte colony-stimulating factor; Csf3; G-CSF |
产品描述 |
Recombinant Mouse Granulocyte Colony-Stimulating Factor is produced by our Mammalian expression system and the target gene encoding Val31-Ala208 is expressed with a 6His tag at the C-terminus. |
分子量 |
Mol Mass:19.8 KDa; APMol Mass:25 KDa, reducing conditions |
剂型描述 |
Lyophilized from a 0.2 μm filtered solution of 10mM Sodium Citrate, 0.1% Tween 20, pH 3.5. |
内毒素 |
< 0.01 EU/µg as determined by LAL test. |
纯度 |
Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
生物活性 |
N/A |
复溶 |
Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
保存条件 |
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.
Reconstituted protein solution can be stored at 2-8°C for 2-7 days.
Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
运输条件 |
The product is shipped at ambient temperature.
Upon receipt, store it immediately at the temperature listed below. |
产品背景 |
Granulocyte colony-stimulating factor (G-CSF) is a growth factor and an essential cytokine which belongs to the IL-6 superfamily. Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. G-CSF binding to its receptor G-CSF-R which belongs to the cytokine receptor type I family depends on the interaction of alpha-helical motifs of the former and two fibronectin type III as well as an immunoglobulin-like domain of the latter. G-CSF is a cytokine that have been demonstrated to improve cardiac function and perfusion in myocardial infarction. And it was initially evaluated as a stem cell mobilizer and erythropoietin as a cytoprotective agent. |