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| 产品名称 | β-Catenin Mouse Monoclonal Antibody(4F2) | 反应种属 | H, R, M |
| 应用 | WB, IHC | ||
| 配方 | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. | ||
| 别称 | beta catenin, b-catenin, CTNB1, CTNNB1, FLJ25606, OTTHUMP00000162082 | ||
| 储存 | -20°C. Do not aliquot the antibody. | ||
| 推荐稀释比 | WB: 1:1,000-2,000 IHC: 1:200-500 Optimal dilutions should be determined by the end user. | ||
| 特异性 | The β-Catenin Mouse Monoclonal antibody detects endogenous β-Catenin proteins. | ||
| 背景信息 | The distinct peripheral cytosolic proteins, alpha, beta and gamma catenin (102, 94 and 86 kDa) are found in many tissues and bind to the conserved cytoplasmic tail domain of the cell adhesion cadherins. Catenins link E cadherin to other integral membrane or cytoplasmic proteins and are modulated by Wnt1 proto oncogene. The central core region of beta catenin is involved in mediation of cadherin catenin complex interaction with EGFR. Beta-Catenin-mediated signalling is involved at several stages of vertebrate neural development. | ||
| 分子量 | ~92KD | 同型 | IgG1 |
| GeneID | 1499 | 理论分子量 | 92 |
| SWISS | P35222 | 宿主物种 | Mouse |
| 免疫原 | Recombinant Protein | 克隆性 | Monoclonal |
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Western blot analysis of 1) Hela, 2) 293T, 3)Mouse Liver Tissue, 4) Rat Liver Tissue, with β-Catenin Mouse mAb diluted at 1:2,000.
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Immunohistochemical analysis of paraffin-embedded Human Lung caricnoma using β-Catenin Mouse mAb diluted at 1:500.