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| 产品名称 | Cofilin 1 Rabbit Polyclonal Antibody(CFL1) | 反应种属 | N/A |
| 应用 | N/A | ||
| 配方 | PBS, pH 7.4, containing 0.02% sodium azide as Preservativeand 50% Glycerol. | ||
| 别称 | CFL1; CFL; Cofilin-1; 18 kDa phosphoprotein; p18; Cofilin; non-muscle isoform | ||
| 储存 | -20°C. Do not aliquot the antibody. | ||
| 推荐稀释比 | WB: 1:2,000-5,000 Optimal dilutions should be determined by the end user. | ||
| 特异性 | Antibody can detects Human endogenous cofilin proteins. | ||
| 背景信息 | Cofilin 1(CFL1) Homo sapiens The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus. | ||
| 分子量 | N/A | 同型 | N/A |
| GeneID | 1072 | 理论分子量 | ~19 |
| SWISS | P23528 | 宿主物种 | Rabbit |
| 免疫原 | Recombinant Protein | 克隆性 | Polyclonal |
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Western blot analysis of 1)Hela Cell, 2) 3T3 Cell, 3)PC12 Cell Lysate using Cofilin Rabbit Polyclonal Antibody diluted at 1:2,000.