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说明书下载产品属性/ Product Details
| 产品名称 | HSD11B1 Rabbit Polyclonal Antibody | 反应种属 | H, M, R |
| 应用 | WB, IHC | ||
| 配方 | PBS, pH 7.4, containing 0.02% sodium azide as Preservativeand 50% Glycerol. | ||
| 别称 | HSD11B1; HSD11; HSD11L; Corticosteroid 11-beta-dehydrogenase isozyme 1; 11-beta-hydroxysteroid dehydrogenase 1; 11-DH; 11-beta-HSD1 | ||
| 储存 | -20°C. Do not aliquot the antibody. | ||
| 推荐稀释比 | WB: 1:1,000-2,000 IHC 1:100-200 Optimal dilutions should be determined by the end user. | ||
| 特异性 | Antibody can detects endogenous HSD11B1 proteins. | ||
| 背景信息 | hydroxysteroid 11-beta dehydrogenase 1(HSD11B1) Homo sapiens The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. | ||
| 分子量 | 35KD | 同型 | IgG |
| GeneID | 3290 | 理论分子量 | 35 |
| SWISS | P28845 | 宿主物种 | Rabbit |
| 免疫原 | N/A | 克隆性 | Polyclonal |
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Western blot analysis of 3T3 Cell Lysate using HSD11B1 Rabbit pAb diluted at 1:2,000.
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Immunohistochemical analysis of paraffin-embedded Human LiverTissue using HSD11B1 Rabbit Polyclonal antibody diluted at 1:200.