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| 产品名称 | Smad3 Mouse Monoclonal Antibody(8B5) | 反应种属 | H,R,M |
| 应用 | WB, IHC | ||
| 配方 | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. | ||
| 别称 | hMAD3 antibody, HSPC193 antibody, LDS1C antibody, MADH3 antibody, JV15 2 antibody | ||
| 储存 | -20°C. Do not aliquot the antibody. | ||
| 推荐稀释比 | WB: 1:1,000-2,000 IHC: 1:100-200 Optimal dilutions should be determined by the end user. | ||
| 特异性 | Antibody can detects endogenous Smad3 protein. | ||
| 背景信息 | Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD3/SMAD4 complex, activates transcription. | ||
| 分子量 | ~50KD | 同型 | IgG1 |
| GeneID | 4088 | 理论分子量 | 52 |
| SWISS | P84022 | 宿主物种 | Mouse |
| 免疫原 | Recombinant Protein | 克隆性 | Monoclonal |
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Western blot analysis of 1)293T, 2)Jurkat, 3)Rat Heart Tissue, 4)Mouse Heart Tissue with Smad3 Mouse mAb diluted at 1:2,000.
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Immunohistochemical analysis of paraffin-embedded Human Liver Tissue using Smad3 Mouse mAb diluted at 1:200.