产品名称 |
MLKL Mouse Monoclonal Antibody(8H7) |
反应种属 |
H |
应用 |
IHC |
配方 |
PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. |
别称 |
Mixed lineage kinase domain like protein, FLJ34389 |
储存 |
-20°C. Do not aliquot the antibody. |
推荐稀释比 |
IHC: 1:100-200
Optimal dilutions should be determined by the end user. |
特异性 |
The antibody can detects endogenous MLKL protein. |
背景信息 |
Mixed lineage kinase domain-like protein (MLKL) is a pseudokinase that was identified as downstream target of RIP3 in the necroptosis pathway. During necroptosis RIP3 is phosphorylated at Ser227, which recruits MLKL and leads to its phosphorylation at Thr357 and Ser358. |
分子量 |
~54KD |
同型 |
IgG1 |
GeneID |
197259 |
理论分子量 |
54 |
SWISS |
Q8NB16 |
宿主物种 |
Mouse |
免疫原 |
Synthetic Peptide |
克隆性 |
Monoclonal |