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| 产品名称 | COX2 Cyclooxygenase 2 Mouse Monoclonal Antibody(2G1) | 反应种属 | H, R, M |
| 应用 | IHC | ||
| 配方 | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. | ||
| 别称 | PTGS2 antibody, Prostaglandin H2 synthase 2 antibody, PGHS 2 antibody, Glucocorticoid-regulated inflammatory cyclooxygenase antibody | ||
| 储存 | -20°C. Do not aliquot the antibody. | ||
| 推荐稀释比 | IHC: 1:100-200 Optimal dilutions should be determined by the end user. | ||
| 特异性 | The COX2 Mouse Monoclonal antibody detects endogenouse COX2 proteins. | ||
| 背景信息 | Prostaglandin-endoperoxide synthase 2, also known as cyclooxygenase-2 or simply COX-2, is an enzyme that in humans is encoded by the PTGS2 gene. There are two isozymes of COX encoded by distinct gene products: a constitutive COX-1 (this enzyme) and an inducible COX-2, which differ in their regulation of expression and tissue distribution. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors. A splice variant of COX-1 termed COX-3 was identified in the CNS of dogs, but does not result in a functional protein in humans. Two smaller COX-1-derived proteins (the partial COX-1 proteins PCOX-1A and PCOX-1B) have also been discovered, but their precise roles are yet to be described. | ||
| 分子量 | 74KD | 同型 | IgG1 |
| GeneID | 5743 | 理论分子量 | 70 |
| SWISS | P35354 | 宿主物种 | Mouse |
| 免疫原 | Synthetic Peptide | 克隆性 | Monoclonal |
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Immunohistochemical analysis of paraffin-embedded Human Colon Carcinoma Tissue using COX-2 Mouse mAb diluted at 1:200.
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Immunohistochemical analysis of paraffin-embedded Human Ovarain Carcinoma Tissue using COX-2 Mouse mAb diluted at 1:200.