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| 产品名称 | P44 42 MAPK(ERK1 2)(Phospho Y205 222) Mouse Monoclonal Antibody(7A6) | 反应种属 | H,R,M |
| 应用 | IHC | ||
| 配方 | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. | ||
| 别称 | MAPK, Mitogen-activated protein Kinase, PRKM2,MK01 | ||
| 储存 | -20°C. Do not aliquot the antibody. | ||
| 推荐稀释比 | IHC: 1:100-200 Optimal dilutions should be determined by the end user. | ||
| 特异性 | The Antibody can detects endogenous P44/42 MAPK(ERK1/2) Phospho Y205/222 proteins. | ||
| 背景信息 | Mitogen-activated protein kinases (MAPKs) are a widely conserved family of serine/threonine protein kinases involved in many cellular programs such as cell proliferation, differentiation, motility, and death. The p44/42 MAPK (Erk1/2) signaling pathway can be activated in response to a diverse range of extracellular stimuli including mitogens, growth factors, and cytokines and is an important target in the diagnosis and treatment of cancer. | ||
| 分子量 | ~44/42KD | 同型 | IgG1 |
| GeneID | 5594/5595 | 理论分子量 | 44,42 |
| SWISS | P27361/P28482 | 宿主物种 | Mouse |
| 免疫原 | Synthetic Peptide | 克隆性 | Monoclonal |
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Immunohistochemical analysis of paraffin-embedded Human Colon Carcinoma Tissue using Phospho-ERK1/2 Mouse mAb diluted at 1:200.
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Immunohistochemical analysis of paraffin-embedded Human Breast Carcinoma Tissue using Phospho-ERK1/2 Mouse mAb diluted at 1:200.