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| 产品名称 | CK19 Mouse Monoclonal Antibody (11F5) | 反应种属 | H,M,R |
| 应用 | IHC | ||
| 配方 | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. | ||
| 别称 | |||
| 储存 | -20°C. Do not aliquot the antibody. | ||
| 推荐稀释比 | IHC: 1:200 Optimal dilutions should be determined by the end user. | ||
| 特异性 | The CK19 Mouse Monoclonal antibody detects endogenous CK19 proteins. | ||
| 背景信息 | This protein is a member of the keratin family. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. Keratin 19 is not expressed in hepatocytes, therefore, antibody to keratin 19 is useful in the identification of liver metastasis. The degree of keratin 19 positivity in breast cancer distinguishes malignant from benign tumours. Keratin 19 is often co-expressed with keratin 7. | ||
| 分子量 | ~44KD | 同型 | IgG1 |
| GeneID | 3880 | 理论分子量 | 44 |
| SWISS | P08727 | 宿主物种 | Mouse |
| 免疫原 | Synthetic Peptide | 克隆性 | Monoclonal |
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IHC staining of human colon cancer tissue with CK19 mouse mAb(11F5) diluted at 1:200.