产品名称 |
P63-α Mouse Monoclonal Antibody(3F11) |
反应种属 |
H, R, M |
应用 |
WB,IHC |
配方 |
PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. |
别称 |
p63, Tumor protein 63 antibody,p53CP |
储存 |
-20°C. Do not aliquot the antibody. |
推荐稀释比 |
WB: 1:1,000~2,000 IHC:1:100~200
Optimal dilutions should be determined by the end user. |
特异性 |
P63-α antibody detects endogenous P63-αproteins. |
背景信息 |
p63 can induce p53-responsive genes and apoptosis, mutation of p63 rarely results in tumors . Research investigators frequently observe amplification of the p63 gene in squamous cell carcinomas of the lung, head and neck . The p63 gene contains an alternative transcription initiation site that yields a 40 kDa δNp63 lacking the transactivation domain, and alternative splicing at the carboxy-terminus yields the α, β, and γ isoforms . |
分子量 |
50~80KD |
同型 |
IgG1 |
GeneID |
8626 |
理论分子量 |
50-80 |
SWISS |
Q9H3D4 |
宿主物种 |
Mouse |
免疫原 |
Synthetic Peptide |
克隆性 |
Monoclonal |