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| 产品名称 | TFE3 Mouse Monoclonal Antibody(8B4) | 反应种属 | H |
| 应用 | IHC | ||
| 配方 | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. | ||
| 别称 | BHLHE33; Transcription factor E3; Class E basic helix-loop-helix protein 33; bHLHe33 | ||
| 储存 | -20°C. Do not aliquot the antibody. | ||
| 推荐稀释比 | IHC 1:100-200 Optimal dilutions should be determined by the end user. | ||
| 特异性 | The antibody detects endogenous TFE3 proteins. | ||
| 背景信息 | transcription factor binding to IGHM enhancer 3(TFE3) Homo sapiens This gene encodes a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences in the promoter of genes. The encoded protein promotes the expression of genes downstream of transforming growth factor beta (TGF-beta) signaling. This gene may be involved in chromosomal translocations in renal cell carcinomas and other cancers, resulting in the production of fusion proteins. Translocation partners include PRCC (papillary renal cell carcinoma), NONO (non-POU domain containing, octamer-binding), and ASPSCR1 (alveolar soft part sarcoma chromosome region, candidate 1), among other genes. | ||
| 分子量 | 62KD | 同型 | IgG1 |
| GeneID | 7030 | 理论分子量 | 62 |
| SWISS | P19532 | 宿主物种 | Mouse |
| 免疫原 | Synthetic Peptide | 克隆性 | Monoclonal |
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Immunohistochemical analysis of paraffin-embedded Human Esophageal Squamous Cell Carcinoma Tissue using TFE3 Mouse mAb diluted at 1:200.