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货号:RA20324
COX1 Cyclooxygenase 1 Rabbit Polyclonal Antibody

规格:

50 μL

100 μL

价格:

¥1100.00

¥1750.00

货期: 3个工作日

产品属性/ Product Details
产品名称 COX1 Cyclooxygenase 1 Rabbit Polyclonal Antibody 反应种属 H
应用 WB, IHC
配方 PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
别称
储存 -20°C. Do not aliquot the antibody.
推荐稀释比 WB: 1:1,000 IHC: 1:100 Optimal dilutions should be determined by the end user.
特异性 The COX1 Rabbit Polyclonal antibody detects endogenous COX1 proteins.
背景信息 Cyclooxygenase-1 (COX-1), also known as prostaglandin G/H synthase 1, prostaglandin-endoperoxide synthase 1 or prostaglandin H2 synthase 1, is an enzyme that in humans is encoded by the PTGS1 gene. There are two isozymes of COX encoded by distinct gene products: a constitutive COX-1 (this enzyme) and an inducible COX-2, which differ in their regulation of expression and tissue distribution. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors. A splice variant of COX-1 termed COX-3 was identified in the CNS of dogs, but does not result in a functional protein in humans. Two smaller COX-1-derived proteins (the partial COX-1 proteins PCOX-1A and PCOX-1B) have also been discovered, but their precise roles are yet to be described.
分子量 ~70KD 同型 IgG
GeneID 5742 理论分子量 70
SWISS P23219 宿主物种 Rabbit
免疫原 Synthetic Peptide 克隆性 Polyclonal
  • Western blot analysis of Hela with COX1 Rabbit Polyclonal antibody diluted at 1:1,000.