规格:
50 μL
100 μL
价格:
¥1100.00
¥1750.00
货期: 3个工作日
产品名称 | COX1 Cyclooxygenase 1 Rabbit Polyclonal Antibody | 反应种属 | H |
应用 | WB, IHC | ||
配方 | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. | ||
别称 | |||
储存 | -20°C. Do not aliquot the antibody. | ||
推荐稀释比 | WB: 1:1,000 IHC: 1:100 Optimal dilutions should be determined by the end user. | ||
特异性 | The COX1 Rabbit Polyclonal antibody detects endogenous COX1 proteins. | ||
背景信息 | Cyclooxygenase-1 (COX-1), also known as prostaglandin G/H synthase 1, prostaglandin-endoperoxide synthase 1 or prostaglandin H2 synthase 1, is an enzyme that in humans is encoded by the PTGS1 gene. There are two isozymes of COX encoded by distinct gene products: a constitutive COX-1 (this enzyme) and an inducible COX-2, which differ in their regulation of expression and tissue distribution. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors. A splice variant of COX-1 termed COX-3 was identified in the CNS of dogs, but does not result in a functional protein in humans. Two smaller COX-1-derived proteins (the partial COX-1 proteins PCOX-1A and PCOX-1B) have also been discovered, but their precise roles are yet to be described. | ||
分子量 | ~70KD | 同型 | IgG |
GeneID | 5742 | 理论分子量 | 70 |
SWISS | P23219 | 宿主物种 | Rabbit |
免疫原 | Synthetic Peptide | 克隆性 | Polyclonal |