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| 产品名称 | CD68 Mouse Monoclonal Antibody(12E2) | 反应种属 | H, R, M |
| 应用 | IHC | ||
| 配方 | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. | ||
| 别称 | CD68 antigen antibody, Macrophage antigen CD68 (microsialin) antibody, GP110 antibody | ||
| 储存 | -20°C. Do not aliquot the antibody. | ||
| 推荐稀释比 | IHC: 1:200-500 Optimal dilutions should be determined by the end user. | ||
| 特异性 | The CD68 antibody can detects endogenous CD68 protein. | ||
| 背景信息 | The CD68 antigen is a 37kD transmembrane protein that is post-translationally glycosylated to give a protein of 87-115kD. CD68 is specifically expressed by tissue macrophages, Langerhans cells and at low levels by dendritic cells. It could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. It binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin bearing substrates or other cells. | ||
| 分子量 | ~37KD | 同型 | IgG1 |
| GeneID | 968 | 理论分子量 | N/A |
| SWISS | P34810 | 宿主物种 | Mouse |
| 免疫原 | Synthetic Peptide | 克隆性 | Monoclonal |
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Immunohistochemical analysis of paraffin-embedded Human Tonsil Tissue using CD68 Mouse mAb diluted at 1:500.